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The primary endpoint was major adverse cardiovascular events (often called MACE), a combined measure of: Cardiovascular death Nonfatal heart attack Nonfatal stroke Over a median follow-up of about 3.5 years, semaglutide reduced the relative risk of these events by about 20% compared with placebo

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Z., Zheng, S

Antagonists: Encouraging Natural Functions An interesting point about GLP-1 medications is that theyre agonists, not antagonists

Both medications help you feel full with less food by slowing gastric emptying and curbing appetite